Pesquisa sobre:
PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 12
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DeCS
Descritor
Inglês
:
Protein Tyrosine Phosphatase, Non-Receptor Type 12
Descritor
Espanhol
:
Proteína Tirosina Fosfatasa no Receptora Tipo 12
Descritor
Português
:
Proteína Tirosina Fosfatase não Receptora Tipo 12
Categoria:
D08.811.277.352.650.775.300.850
D12.644.360.585.850
D12.776.476.564.850
Definição
Inglês
:
A subtype of non-receptor
protein tyrosine phosphatases
that is characterized by the presence of a N-terminal
catalytic domain
and a large C-terminal domain that is enriched in
PROLINE
,
GLUTAMIC ACID
,
SERINE
, and
THREONINE
residues (PEST sequences). The phosphatase subtype is ubiquitously expressed and implicated in the regulation of a variety of biological processes such as
CELL MOVEMENT
;
CYTOKINESIS
; focal adhesion disassembly; and
LYMPHOCYTE ACTIVATION.
Nota Histórica
Inglês
:
2008(1994)
Qualificadores Permitidos
Inglês
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Número do Registro:
52701
Identificador Único:
D054594
Ocorrência na BVS
:
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